The Quiet Spike is a telescoping forward fuselage extension that alters the bow shock of the classic N-wave pressure signature generated by aircraft travelling at supersonic speed. The bow shock is broken up into sequence of weak shocks that parallel to each other with coalescing. Supersonic airliner of the "shuttle" layout is analyzed in the paper. Based on CFD and waveform parameter method, different geometrical parameters of multi-segment quiet spikes are studied. The results demonstrate that the impact of quiet spike to supersonic airliner’s sonic boom is remarkable. The sonic boom is reduced distinctly by well-designed quiet spike. The sonic boom is remarkable affected by the segments. The well-designed multi-segment quiet spike has better capability for reducing the sonic boom than single-segment quiet spike.