Abstract: As the fatigue life of airborne evaporation circulatory system structure is susceptible to the influence of external and internal environment, it does not satisfy the design requirements. Based on stochastic finite element method and considering the variability of design variables and other random variables, a mathematic model of the robustness optimization of fatigue life is established. As the robustness optimization of fatigue life of the airborne evaporation circulatory system structure robust optimization is studied, the robustness of fatigue life problem is transformed into the double objective problems of mean and standard deviation of fatigue life, which effectively reduces the sensitivity of the design variables for fatigue life and improves the robustness of fatigue life by setting the power factor of mean and standard deviation of fatigue life.