Complicated calculation process and low calculation efficiency are main challenges for reliability analysis of complex structures assembled from multiple components. Moving extremum response surface method-based decomposed coordinative strategy (DCMERSM, short for) is proposed based on extremum response surface method, moving least squares and decomposition coordinative strategy, which is used to accomplish dynamic reliability analysis of multi-component structures. In this paper, the dynamic reliability analysis of the radial deformation of the high-pressure turbine blade disk (composed of blades and wheel disks) of the aeroengine considering the effect of fluid-thermal-structural coupling, and the direct simulation and decomposed coordinative extremum response surface method (DCERSM) are compared to illustrate the effectiveness and applicability of the proposed DCMERSM in modeling characteristics and simulation performance. The developed DCMERSM is not only suitable for the dynamic reliability analysis of rotor machinery, but also for the reliability analysis of multi-component structures of complex machinery.