Variable camber wing structure is becoming a research hotspot. In this paper, a mathematical model is established for the rigid-flexible coupling type of continuously varying cambour trailing edge structure, and the Latin hypercube sampling method is used for stratified sampling, the correlation vector machine algorithm is used to build the model, and the differential optimization algorithm is used to optimize the model. According to the calculation results, the optimized rigid-flexible coupling skin improves the deformation accuracy by 67%, and the correlation coefficient of each variable to the deformation error is analyzed, which provides a reference for the design.