The angle-of-attack signal is very important for modern fly-by-wire flight control system aircrafts. The inconsistency of the local airflow on both sides of the nose will cause the difference of the angle-of-attack signal. The signal-monitoring logic of the flight control system will judge the angle-of-attack signal and make the angle-of-attack availability decrease. By studying the relationship between the lateral overload and the side slip angle, the side slip angle is estimated by the lateral overload, and the angle of attack signal correction method based on the side slip angle estimation is established to improve the availability of the angle of attack signal under the condition of large side slip. The simulation results show that the proposed method is successful in estimating the side-slip angle, and the angle-of-attack signal on both sides of the nose is consistent with the modified side-slip angle, which solves the problem of over-error of the angle-of-attack signal caused by the large side-slip state and has good correction effect.